Our PCCMS

TOXPRO     TARGET DISCOVERY AND CHARACTERIZATION    COLLABORATIONS 


Primary structure or expression level differences of proteins in disease versus healthy cells are thus rapidly screened using mass spectrometry. The disease relevance of these potential targets is next determined using various cell based and biochemical assays to understand the cellular function of those proteins that show the structural differences.Many diseases are associated with variations from normal in the structure of certain proteins.

CCMS™ is used to determine differences in the structure of proteins derived from healthy versus disease cells. HK Pharmaceuticals’ proprietary library of synthetic Capture Compounds exploits the vastly different chemical/physical properties of regions on a protein’s outer surface to selectively capture it by a chemical means, separating individual or closely related proteins from complex biological mixtures.